Association of rs182429 variant in TAGAP with rheumatoid arthritis in Pakistani population
نویسندگان
چکیده
منابع مشابه
comparative evaluation of heavy metals in patients with rheumatoid arthritis and healthy control in pakistani population
background: exposure to heavy metals in development of many diseases has been investigated previously, specially created by oxidative stress. the etiology of rheumatoid arthritis (ra) is still not fully understood but oxidative stress created by heavy metals may have role in development of ra. the aim of present study was to compare serum level of heavy metals in ra and healthy control individu...
متن کاملAssociation of HLA-DRB1 and -DQB1alleles and haplotypes with rheumatoid arthritis in a Pakistani population
INTRODUCTION Rheumatoid arthritis is an autoimmune disease with poorly understood pathophysiology. Genetic components of disease etiology, especially human leukocyte antigen (HLA) associations, are well known. Ethnic differences account for a number of variations in disease association with the HLA locus and there seem to be differences in various studies regarding its genetic predisposition. T...
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Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific skin lesions of RA such as rheumatoid nodules, exacerbated nodules, rheumatoid vascu...
متن کاملHearing status in patients with rheumatoid arthritis
Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...
متن کاملAssociation of PTPN22 rs2476601 Polymorphism with Rheumatoid Arthritis and Celiac Disease in Khuzestan Province, Southwestern Iran
Background: Single-nucleotide polymorphism (SNP) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (PTPN22) has been shown to be a risk factor for different autoimmune diseases. This study explored the association of 1858 C/T SNP with rheumatoid arthritis (RA) and celiac disease (CD) in a region covering south-west of Iran. Methods: Totally, 52 patients with CD, 120 patien...
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ژورنال
عنوان ژورنال: Meta Gene
سال: 2017
ISSN: 2214-5400
DOI: 10.1016/j.mgene.2017.08.003